Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

Lung adenocarcinomas (LUADs) with somatic mutations in the KRAS oncogene comprise the most common molecular subtype of lung cancer in smokers and present with overall dismal prognosis and resistance to most therapies. Our group recently demonstrated that tobacco carcinogen-exposed mice with knockout...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Daouk, Reem, Hassane, Maya, Bahmad, Hisham F., Sinjab, Ansam, Fujimoto, Junya, Abou-Kheir, Wassim, Kadara, Humam
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454871/
https://ncbi.nlm.nih.gov/pubmed/31001473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00207
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