Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

Lung adenocarcinomas (LUADs) with somatic mutations in the KRAS oncogene comprise the most common molecular subtype of lung cancer in smokers and present with overall dismal prognosis and resistance to most therapies. Our group recently demonstrated that tobacco carcinogen-exposed mice with knockout...

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Bibliographic Details
Published in:Front Oncol
Main Authors: Daouk, Reem, Hassane, Maya, Bahmad, Hisham F., Sinjab, Ansam, Fujimoto, Junya, Abou-Kheir, Wassim, Kadara, Humam
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2019
Subjects:
Oncology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454871/
https://ncbi.nlm.nih.gov/pubmed/31001473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00207
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