Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations

Lung adenocarcinomas (LUADs) with somatic mutations in the KRAS oncogene comprise the most common molecular subtype of lung cancer in smokers and present with overall dismal prognosis and resistance to most therapies. Our group recently demonstrated that tobacco carcinogen-exposed mice with knockout...

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Bibliographische Detailangaben
Veröffentlicht in:Front Oncol
Hauptverfasser: Daouk, Reem, Hassane, Maya, Bahmad, Hisham F., Sinjab, Ansam, Fujimoto, Junya, Abou-Kheir, Wassim, Kadara, Humam
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6454871/
https://ncbi.nlm.nih.gov/pubmed/31001473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2019.00207
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