Comparative Functional Genomics Analysis of NNK Tobacco-Carcinogen Induced Lung Adenocarcinoma Development in Gprc5a-Knockout Mice

BACKGROUND: Improved understanding of lung cancer development and progression, including insights from studies of animal models, are needed to combat this fatal disease. Previously, we found that mice with a knockout (KO) of G-protein coupled receptor 5A (Gprc5a) develop lung tumors after a long lat...

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Detalhes bibliográficos
Main Authors: Fujimoto, Junya, Kadara, Humam, Men, Taoyan, van Pelt, Carolyn, Lotan, Dafna, Lotan, Reuben
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2912294/
https://ncbi.nlm.nih.gov/pubmed/20686609
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0011847
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