Development of Kras mutant lung adenocarcinoma in mice with knockout of the airway lineage-specific gene Gprc5a

Despite the urgency for prevention and treatment of lung adenocarcinoma (LUAD), we still do not know drivers in pathogenesis of the disease. Earlier work revealed that mice with knockout of the G-protein coupled receptor Gprc5a develop late onset lung tumors including LUADs. Here, we sought to furth...

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Publicado en:Int J Cancer
Autores principales: Fujimoto, Junya, Nunomura-Nakamura, Sayuri, Liu, Yihua, Lang, Wenhua, McDowell, Tina, Jakubek, Yasminka, Ezzeddine, Dalia, Ochieng, Joshua Kapere, Petersen, Jason, Davies, Gareth, Fukuoka, Junya, Wistuba, Ignacio I., Ehli, Erik, Fowler, Jerry, Scheet, Paul, Kadara, Humam
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774849/
https://ncbi.nlm.nih.gov/pubmed/28653505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.30851
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