טוען...
Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion
Conventional cytotoxic chemotherapy is highly effective in certain cancers, but causes dose-limiting damage to normal proliferating cells, especially hematopoietic stem and progenitor cells (HSPCs). Serial exposure to cytotoxics causes a long-term hematopoietic compromise (‘exhaustion’), which limit...
שמור ב:
| הוצא לאור ב: | Sci Transl Med |
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| Main Authors: | , , , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2017
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5774632/ https://ncbi.nlm.nih.gov/pubmed/28446688 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aal3986 |
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