Half-life prolongation of therapeutic proteins by conjugation to ATIII-binding pentasaccharides: a first-in-human study of CarboCarrier® insulin

Por Miltenburg, André M M, Prohn, Marita, Kuijk, Jacqueline H M, Tiessen, Renger G, Kort, Martin, Berg, Rob J W
Publicado em 2013

Safety, tolerability and pharmacodynamics of apical sodium-dependent bile acid transporter inhibition with volixibat in healthy adults and patients with type 2 diabetes mellitus: a...

Por Tiessen, Renger G., Kennedy, Ciara A., Keller, Bradley T., Levin, Nancy, Acevedo, Lisette, Gedulin, Bronislava, van Vliet, Andre A., Dorenbaum, Alejandro, Palmer, Melissa
Publicado no BMC Gastroenterol (2018)

Transient CDK4/6 inhibition protects hematopoietic stem cells from chemotherapy-induced exhaustion

Por He, Shenghui, Roberts, Patrick J., Sorrentino, Jessica A., Bisi, John E., Storrie-White, Hannah, Tiessen, Renger G., Makhuli, Karenann M., Wargin, William A., Tadema, Henko, van Hoogdalem, Ewoud-Jan, Strum, Jay C., Malik, Rajesh, Sharpless, Norman E.
Publicado no Sci Transl Med (2017)