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Hes1 deficiency causes hematopoietic stem cell exhaustion
The transcriptional repressor Hairy Enhancer of Split 1 (HES1) plays an essential role in the development of many organs by promoting the maintenance of stem/progenitor cells, controlling the reversibility of cellular quiescence, and regulating both cell fate decisions. Deletion of Hes1 in mice resu...
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| Publicat a: | Stem Cells |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
John Wiley & Sons, Inc.
2020
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7260087/ https://ncbi.nlm.nih.gov/pubmed/32129527 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3169 |
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