Hes1 deficiency causes hematopoietic stem cell exhaustion

The transcriptional repressor Hairy Enhancer of Split 1 (HES1) plays an essential role in the development of many organs by promoting the maintenance of stem/progenitor cells, controlling the reversibility of cellular quiescence, and regulating both cell fate decisions. Deletion of Hes1 in mice resu...

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Detalhes bibliográficos
Publicado no:Stem Cells
Main Authors: Ma, Zhilin, Xu, Jian, Wu, Limei, Wang, Junjie, Lin, Qiqi, Chowdhury, Fabliha A., Mazumder, Md. Habibul H., Hu, Gangqing, Li, Xue, Du, Wei
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Stem Cell Technology: Epigenetics, Genomics, Proteomics and Metabonomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7260087/
https://ncbi.nlm.nih.gov/pubmed/32129527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.3169
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