Persistent DNA damage–induced NLRP12 improves hematopoietic stem cell function

NOD-like receptor 12 (NLRP12) is a member of the nucleotide-binding domain and leucine-rich repeat containing receptor inflammasome family that plays a central role in innate immunity. We previously showed that DNA damage upregulated NLRP12 in hematopoietic stem cells (HSCs) of mice deficient in the...

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Detaylı Bibliyografya
Yayımlandı:JCI Insight
Asıl Yazarlar: Lin, Qiqi, Wu, Limei, Ma, Zhilin, Chowdhury,1, Fabliha Ahmed, Mazumder, Habibul Hasan, Du, Wei
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Clinical Investigation 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7259522/
https://ncbi.nlm.nih.gov/pubmed/32434992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.133365
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