Nrf2 Deficiency Upregulates Intrarenal Angiotensin-Converting Enzyme-2 and Angiotensin 1-7 Receptor Expression and Attenuates Hypertension and Nephropathy in Diabetic Mice

We investigated the role of nuclear factor erythroid 2–related factor 2 (Nrf2) in renin-angiotensin system (RAS) gene expression in renal proximal tubule cells (RPTCs) and in the development of systemic hypertension and kidney injury in diabetic Akita mice. We used adult male Akita Nrf2 knockout mic...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Endocrinology
Hoofdauteurs: Zhao, Shuiling, Ghosh, Anindya, Lo, Chao-Sheng, Chenier, Isabelle, Scholey, James W., Filep, Janos G., Ingelfinger, Julie R., Zhang, Shao-Ling, Chan, John S. D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Endocrine Society 2017
Onderwerpen:
Research Articles
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5774246/
https://ncbi.nlm.nih.gov/pubmed/29211853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2017-00752
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items