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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b

Gating of the mammalian inward rectifier Kir1.1 at the helix bundle crossing (HBC) by intracellular pH is believed to be mediated by conformational changes in the C-terminal domain (CTD). However, the exact motion of the CTD during Kir gating remains controversial. Crystal structures and single-mole...

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Detalles Bibliográficos
Publicado en:Biophys J
Autores principales: Nanazashvili, Mikheil, Sánchez-Rodríguez, Jorge E., Fosque, Ben, Bezanilla, Francisco, Sackin, Henry
Formato: Artigo
Lenguaje:Inglês
Publicado: The Biophysical Society 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773755/
https://ncbi.nlm.nih.gov/pubmed/29320699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.044
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