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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b

Gating of the mammalian inward rectifier Kir1.1 at the helix bundle crossing (HBC) by intracellular pH is believed to be mediated by conformational changes in the C-terminal domain (CTD). However, the exact motion of the CTD during Kir gating remains controversial. Crystal structures and single-mole...

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Dettagli Bibliografici
Pubblicato in:Biophys J
Autori principali: Nanazashvili, Mikheil, Sánchez-Rodríguez, Jorge E., Fosque, Ben, Bezanilla, Francisco, Sackin, Henry
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Biophysical Society 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773755/
https://ncbi.nlm.nih.gov/pubmed/29320699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.044
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