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External K Activation of Kir1.1 Depends on the pH Gate
The inward rectifier Kir1.1 (ROMK) family is gated by both internal pH and external K, where the putative pH gate is formed by the convergence of leucine side chains, near the inner helical bundle crossing at L160-Kir1.1. However, it is unclear whether K activation is mediated at the pH gate or by a...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The Biophysical Society
2007
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1896244/ https://ncbi.nlm.nih.gov/pubmed/17496015 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110122 |
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