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Role of Conserved Glycines in pH Gating of Kir1.1 (ROMK)
Gating of inward rectifier Kir1.1 potassium channels by internal pH is believed to occur when large hydrophobic leucines, on each of the four subunits, obstruct the permeation path at the cytoplasmic end of the inner transmembrane helices (TM2). In this study, we examined whether closure of the chan...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Biophysical Society
2006
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1440738/ https://ncbi.nlm.nih.gov/pubmed/16533837 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.076653 |
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