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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b

Gating of the mammalian inward rectifier Kir1.1 at the helix bundle crossing (HBC) by intracellular pH is believed to be mediated by conformational changes in the C-terminal domain (CTD). However, the exact motion of the CTD during Kir gating remains controversial. Crystal structures and single-mole...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Nanazashvili, Mikheil, Sánchez-Rodríguez, Jorge E., Fosque, Ben, Bezanilla, Francisco, Sackin, Henry
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773755/
https://ncbi.nlm.nih.gov/pubmed/29320699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.044
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