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LRET Determination of Molecular Distances during pH Gating of the Mammalian Inward Rectifier Kir1.1b

Gating of the mammalian inward rectifier Kir1.1 at the helix bundle crossing (HBC) by intracellular pH is believed to be mediated by conformational changes in the C-terminal domain (CTD). However, the exact motion of the CTD during Kir gating remains controversial. Crystal structures and single-mole...

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Dades bibliogràfiques
Publicat a:Biophys J
Autors principals: Nanazashvili, Mikheil, Sánchez-Rodríguez, Jorge E., Fosque, Ben, Bezanilla, Francisco, Sackin, Henry
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2018
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5773755/
https://ncbi.nlm.nih.gov/pubmed/29320699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.044
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