تحميل...
Dynamic Structural Differences between Human and Mouse STING Lead to Differing Sensitivity to DMXAA
The stimulator-of-interferon-genes (STING) protein is involved in innate immunity. It has recently been shown that modulation of STING can lead to an aggressive antitumor response. DMXAA is an antitumor agent that had shown great promise in murine models but failed in human clinical trials. The mole...
محفوظ في:
| الحاوية / القاعدة: | Biophys J |
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| المؤلفون الرئيسيون: | , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
The Biophysical Society
2018
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5773749/ https://ncbi.nlm.nih.gov/pubmed/29320694 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.10.027 |
| الوسوم: |
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