The STING agonist DMXAA triggers a cooperation between T lymphocytes and myeloid cells that leads to tumor regression

Regressing tumors are usually associated with a large immune infiltrate, but the molecular and cellular interactions that govern a successful anti-tumor immunity remain elusive. Here, we have triggered type I Interferon (IFN) signaling in a breast tumor model (MMTV-PyMT) using 5,6-dimethylxanthenone...

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Detalles Bibliográficos
Publicado en:Oncoimmunology
Main Authors: Weiss, Julia M., Guérin, Marion V., Regnier, Fabienne, Renault, Gilles, Galy-Fauroux, Isabelle, Vimeux, Lene, Feuillet, Vincent, Peranzoni, Elisa, Thoreau, Maxime, Trautmann, Alain, Bercovici, Nadège
Formato: Artigo
Idioma:Inglês
Publicado: Taylor & Francis 2017
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665074/
https://ncbi.nlm.nih.gov/pubmed/29123960
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2017.1346765
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