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TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors
Type I interferons (IFN) are being rediscovered as potent anti-tumoral agents. Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce strong production of IFNα/β and rejection of transplanted primary tumors. In the present study, we addres...
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| 發表在: | Nat Commun |
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| Main Authors: | , , , , , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739328/ https://ncbi.nlm.nih.gov/pubmed/31511510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11998-w |
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