TGFβ blocks IFNα/β release and tumor rejection in spontaneous mammary tumors

Type I interferons (IFN) are being rediscovered as potent anti-tumoral agents. Activation of the STimulator of INterferon Genes (STING) by DMXAA (5,6-dimethylxanthenone-4-acetic acid) can induce strong production of IFNα/β and rejection of transplanted primary tumors. In the present study, we addres...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Guerin, Marion V., Regnier, Fabienne, Feuillet, Vincent, Vimeux, Lene, Weiss, Julia M., Bismuth, Georges, Altan-Bonnet, Gregoire, Guilbert, Thomas, Thoreau, Maxime, Finisguerra, Veronica, Donnadieu, Emmanuel, Trautmann, Alain, Bercovici, Nadège
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739328/
https://ncbi.nlm.nih.gov/pubmed/31511510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11998-w
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados