The lysine acetyltransferase GCN5 is required for iNKT cell development through EGR2 acetylation

The development of CD1d-restricted invariant NKT (iNKT) cells, a population that is critical for both innate and adaptive immunity, is regulated by multiple transcription factors, but the molecular mechanisms underlying how the transcriptional activation of these factors are regulated during iNKT de...

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Veröffentlicht in:Cell Rep
Hauptverfasser: Wang, Yajun, Yun, Chawon, Gao, Beixue, Xu, Yuanming, Zhang, Yana, Wang, Yiming, Kong, Qingfei, Zhao, Fang, Wang, Chyung-Ru, Dent, Sharon Y.R., Wang, Jian, Xu, Xiangping, Li, Hua-Bin, Fang, Deyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772774/
https://ncbi.nlm.nih.gov/pubmed/28723564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.065
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