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Increased level of E protein activity during iNKT development promotes differentiation of iNKT2 and iNKT17 subsets
E protein transcription factors, and their natural inhibitors, Id proteins, play critical and complex roles during lymphoid development. Here we report that partial maintenance of E protein activity during positive selection results in a change in the cell fate determination of developing iNKT cells...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3832958/ https://ncbi.nlm.nih.gov/pubmed/24123679 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1301546 |
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