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The lysine acetyltransferase GCN5 is required for iNKT cell development through EGR2 acetylation

The development of CD1d-restricted invariant NKT (iNKT) cells, a population that is critical for both innate and adaptive immunity, is regulated by multiple transcription factors, but the molecular mechanisms underlying how the transcriptional activation of these factors are regulated during iNKT de...

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Pubblicato in:Cell Rep
Autori principali: Wang, Yajun, Yun, Chawon, Gao, Beixue, Xu, Yuanming, Zhang, Yana, Wang, Yiming, Kong, Qingfei, Zhao, Fang, Wang, Chyung-Ru, Dent, Sharon Y.R., Wang, Jian, Xu, Xiangping, Li, Hua-Bin, Fang, Deyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5772774/
https://ncbi.nlm.nih.gov/pubmed/28723564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.06.065
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