Φορτώνει......
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs
Development of biased ligands targeting G protein-coupled receptors (GPCRs) is a promising approach for current drug discovery. Although structure-based drug design of biased agonists remains challenging even with an abundance of GPCR crystal structures, we present an approach for translating GPCR s...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Nat Chem Biol |
|---|---|
| Κύριοι συγγραφείς: | , , , , , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2017
|
| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771956/ https://ncbi.nlm.nih.gov/pubmed/29227473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2527 |
| Ετικέτες: |
Προσθήκη ετικέτας
Δεν υπάρχουν, Καταχωρήστε ετικέτα πρώτοι!
|