Cargando...
Structure-inspired design of β-arrestin-biased ligands for aminergic GPCRs
Development of biased ligands targeting G protein-coupled receptors (GPCRs) is a promising approach for current drug discovery. Although structure-based drug design of biased agonists remains challenging even with an abundance of GPCR crystal structures, we present an approach for translating GPCR s...
Gardado en:
| Publicado en: | Nat Chem Biol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2017
|
| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771956/ https://ncbi.nlm.nih.gov/pubmed/29227473 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2527 |
| Tags: |
Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!
|