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GPCRs and arrestins in airways: implications for asthma

The obstructive lung disease asthma is treated by drugs that target, either directly or indirectly, G protein-coupled receptors (GPCRs). GPCRs coupled to Gq are the primary mediators of airway smooth muscle (ASM) contraction and increased airway resistance, whereas the Gs-coupled beta-2-adrenoceptor...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Handb Exp Pharmacol
Egile Nagusiak: Penn, Raymond B., Bond, Richard A., Walker, Julia K. L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4429126/
https://ncbi.nlm.nih.gov/pubmed/24292841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-41199-1_20
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