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GPCRs and arrestins in airways: implications for asthma
The obstructive lung disease asthma is treated by drugs that target, either directly or indirectly, G protein-coupled receptors (GPCRs). GPCRs coupled to Gq are the primary mediators of airway smooth muscle (ASM) contraction and increased airway resistance, whereas the Gs-coupled beta-2-adrenoceptor...
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| Publicado no: | Handb Exp Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4429126/ https://ncbi.nlm.nih.gov/pubmed/24292841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-642-41199-1_20 |
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