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Genetic Deletion of β-Arrestin-2 and the Mitigation of Established Airway Hyperresponsiveness in a Murine Asthma Model
β-Arrestin-2 (βarr2) is a ubiquitously expressed cytosolic protein that terminates G protein–coupled receptor signaling and transduces G protein–independent signaling. We previously showed that mice lacking βarr2 do not develop an asthma phenotype when sensitized to, and challenged with, allergens....
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Publicado no: | Am J Respir Cell Mol Biol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Thoracic Society
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4566063/ https://ncbi.nlm.nih.gov/pubmed/25569510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2014-0231OC |
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