β-Arrestin2 mediates progression of murine primary myelofibrosis

Primary myelofibrosis is a myeloproliferative neoplasm associated with significant morbidity and mortality, for which effective therapies are lacking. β-Arrestins are multifunctional adaptor proteins involved in developmental signaling pathways. One isoform, β-arrestin2 (βarr2), has been implicated...

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Detalhes bibliográficos
Publicado no:JCI Insight
Main Authors: Rein, Lindsay A.M., Wisler, James W., Kim, Jihee, Theriot, Barbara, Huang, LiYin, Price, Trevor, Yang, Haeyoon, Chen, Minyong, Chen, Wei, Sipkins, Dorothy, Fedoriw, Yuri, Walker, Julia K.L., Premont, Richard T., Lefkowitz, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5752278/
https://ncbi.nlm.nih.gov/pubmed/29263312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.98094
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