β-Arrestin-mediated Signaling Regulates Protein Synthesis

Seven transmembrane receptors (7TMRs) exert strong regulatory influences on virtually all physiological processes. Although it is historically assumed that heterotrimeric G proteins mediate these actions, there is a newer appreciation that β-arrestins, originally thought only to desensitize G protei...

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Bibliographic Details
Main Authors: DeWire, Scott M., Kim, Jihee, Whalen, Erin J., Ahn, Seungkirl, Chen, Minyong, Lefkowitz, Robert J.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2008
Subjects:
Mechanisms of Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2447657/
https://ncbi.nlm.nih.gov/pubmed/18276584
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M710515200
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