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Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy
The development of effective antifungal therapeutics remains a formidable challenge due to the close evolutionary relationship between humans and fungi. Mitochondrial function may present an exploitable vulnerability due to its differential utilization in fungi and its pivotal roles in fungal morpho...
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| Publié dans: | Nat Chem Biol |
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| Auteurs principaux: | , , , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5771894/ https://ncbi.nlm.nih.gov/pubmed/29227471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2534 |
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