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Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

The development of effective antifungal therapeutics remains a formidable challenge due to the close evolutionary relationship between humans and fungi. Mitochondrial function may present an exploitable vulnerability due to its differential utilization in fungi and its pivotal roles in fungal morpho...

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Publicado en:Nat Chem Biol
Autores principales: McLellan, Catherine A., Vincent, Benjamin M., Solis, Norma V., Lancaster, Alex K., Sullivan, Lucas B., Hartland, Cathy L., Youngsaye, Willmen, Filler, Scott G., Whitesell, Luke, Lindquist, Susan
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771894/
https://ncbi.nlm.nih.gov/pubmed/29227471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2534
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