Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy

The development of effective antifungal therapeutics remains a formidable challenge due to the close evolutionary relationship between humans and fungi. Mitochondrial function may present an exploitable vulnerability due to its differential utilization in fungi and its pivotal roles in fungal morpho...

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Bibliographic Details
Published in:Nat Chem Biol
Main Authors: McLellan, Catherine A., Vincent, Benjamin M., Solis, Norma V., Lancaster, Alex K., Sullivan, Lucas B., Hartland, Cathy L., Youngsaye, Willmen, Filler, Scott G., Whitesell, Luke, Lindquist, Susan
Format: Artigo
Language:Inglês
Published: 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771894/
https://ncbi.nlm.nih.gov/pubmed/29227471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.2534
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