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Correlation of Cellular Factors and Differential Scrapie Prion Permissiveness in Ovine Microglia

Prion diseases are fatal neurodegenerative disorders by which the native cellular prion protein (PrP(C)) is misfolded into an accumulating, disease-associated isoform (PrP(D)). To improve the understanding of prion pathogenesis and develop effective treatments, it is essential to elucidate factors c...

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Bibliographische Detailangaben
Veröffentlicht in:Virus Res
Hauptverfasser: Dinkel, Kelcey D., Schneider, David A., Muñoz-Gutiérrez, Juan F., McElliott, Valerie R., Stanton, James B.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771472/
https://ncbi.nlm.nih.gov/pubmed/28754560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2017.07.016
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