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Correlation of Cellular Factors and Differential Scrapie Prion Permissiveness in Ovine Microglia

Prion diseases are fatal neurodegenerative disorders by which the native cellular prion protein (PrP(C)) is misfolded into an accumulating, disease-associated isoform (PrP(D)). To improve the understanding of prion pathogenesis and develop effective treatments, it is essential to elucidate factors c...

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Detalles Bibliográficos
Publicado en:Virus Res
Main Authors: Dinkel, Kelcey D., Schneider, David A., Muñoz-Gutiérrez, Juan F., McElliott, Valerie R., Stanton, James B.
Formato: Artigo
Idioma:Inglês
Publicado: 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771472/
https://ncbi.nlm.nih.gov/pubmed/28754560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2017.07.016
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