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Correlation of Cellular Factors and Differential Scrapie Prion Permissiveness in Ovine Microglia

Prion diseases are fatal neurodegenerative disorders by which the native cellular prion protein (PrP(C)) is misfolded into an accumulating, disease-associated isoform (PrP(D)). To improve the understanding of prion pathogenesis and develop effective treatments, it is essential to elucidate factors c...

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Bibliografiske detaljer
Udgivet i:Virus Res
Main Authors: Dinkel, Kelcey D., Schneider, David A., Muñoz-Gutiérrez, Juan F., McElliott, Valerie R., Stanton, James B.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771472/
https://ncbi.nlm.nih.gov/pubmed/28754560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2017.07.016
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