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Correlation of Cellular Factors and Differential Scrapie Prion Permissiveness in Ovine Microglia

Prion diseases are fatal neurodegenerative disorders by which the native cellular prion protein (PrP(C)) is misfolded into an accumulating, disease-associated isoform (PrP(D)). To improve the understanding of prion pathogenesis and develop effective treatments, it is essential to elucidate factors c...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Dinkel, Kelcey D., Schneider, David A., Muñoz-Gutiérrez, Juan F., McElliott, Valerie R., Stanton, James B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5771472/
https://ncbi.nlm.nih.gov/pubmed/28754560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2017.07.016
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