Baseline peripheral blood biomarkers associated with clinical outcome of advanced melanoma patients treated with ipilimumab

PURPOSE: To identify baseline peripheral blood biomarkers associated with clinical outcome following ipilimumab treatment in advanced melanoma patients. EXPERIMENTAL DESIGN: Frequencies of myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs), serum lactate dehydrogenase (LDH), rou...

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Gepubliceerd in:Clin Cancer Res
Hoofdauteurs: Martens, Alexander, Wistuba-Hamprecht, Kilian, Foppen, Marnix Geukes, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Romano, Emanuela, Khammari, Amir, Dreno, Brigitte, Capone, Mariaelena, Ascierto, Paolo A., Di Giacomo, Anna Maria, Maio, Michele, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Hassel, Jessica C., Eigentler, Thomas K., Martus, Peter, Wolchok, Jedd D., Blank, Christian, Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770142/
https://ncbi.nlm.nih.gov/pubmed/26787752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2412
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