Baseline peripheral blood biomarkers associated with clinical outcome of advanced melanoma patients treated with ipilimumab

PURPOSE: To identify baseline peripheral blood biomarkers associated with clinical outcome following ipilimumab treatment in advanced melanoma patients. EXPERIMENTAL DESIGN: Frequencies of myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs), serum lactate dehydrogenase (LDH), rou...

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Vydáno v:Clin Cancer Res
Hlavní autoři: Martens, Alexander, Wistuba-Hamprecht, Kilian, Foppen, Marnix Geukes, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Romano, Emanuela, Khammari, Amir, Dreno, Brigitte, Capone, Mariaelena, Ascierto, Paolo A., Di Giacomo, Anna Maria, Maio, Michele, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Hassel, Jessica C., Eigentler, Thomas K., Martus, Peter, Wolchok, Jedd D., Blank, Christian, Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770142/
https://ncbi.nlm.nih.gov/pubmed/26787752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2412
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