Baseline peripheral blood biomarkers associated with clinical outcome of advanced melanoma patients treated with ipilimumab

PURPOSE: To identify baseline peripheral blood biomarkers associated with clinical outcome following ipilimumab treatment in advanced melanoma patients. EXPERIMENTAL DESIGN: Frequencies of myeloid-derived suppressor cells (MDSCs) and regulatory T cells (Tregs), serum lactate dehydrogenase (LDH), rou...

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Publicat a:Clin Cancer Res
Autors principals: Martens, Alexander, Wistuba-Hamprecht, Kilian, Foppen, Marnix Geukes, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Romano, Emanuela, Khammari, Amir, Dreno, Brigitte, Capone, Mariaelena, Ascierto, Paolo A., Di Giacomo, Anna Maria, Maio, Michele, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Hassel, Jessica C., Eigentler, Thomas K., Martus, Peter, Wolchok, Jedd D., Blank, Christian, Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5770142/
https://ncbi.nlm.nih.gov/pubmed/26787752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-15-2412
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