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Ipilimumab in patients with melanoma and autoimmune disease

Cytotoxic T-Lymphocyte Antigen 4 (CTLA-4), an immune-checkpoint receptor and regulator of T-cell activation, has become an important therapeutic target for immunotherapy in cancer and autoimmune diseases. To date, clinical trials involving cancer immunotherapies, such checkpoint blocking antibodies...

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Podrobná bibliografie
Hlavní autoři: Kyi, Chrisann, Carvajal, Richard D, Wolchok, Jedd D, Postow, Michael A
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4207313/
https://ncbi.nlm.nih.gov/pubmed/25349698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-014-0035-z
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