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Checkpoint Modulation in Melanoma: An Update on Ipilimumab and Future Directions
Ipilimumab, an anti-cytotoxic T-lymphocyte antigen 4 antibody, was the first therapy demonstrated to improve overall survival in melanoma. Since ipilimumab’s approval by the FDA in 2011, a wealth of data have amassed, helping clinicians to optimize its use. We have learned how to mitigate the advers...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3799873/ https://ncbi.nlm.nih.gov/pubmed/23933888 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11912-013-0337-1 |
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