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Immunomodulatory Therapy for Melanoma: Ipilimumab and Beyond
In 2011, the FDA approved the first new therapy for melanoma in over a decade, ipilimumab (Yervoy). Ipilimumab is a novel antibody that blockscytotoxic T lymphocyte-associated antigen 4 (CTLA-4), a regulatory molecule expressed on activated T cells. Blockade of this important immune checkpoint can l...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3653249/ https://ncbi.nlm.nih.gov/pubmed/23438382 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.clindermatol.2012.08.006 |
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