Increases in Absolute Lymphocytes and Circulating CD4(+) and CD8(+) T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab

PURPOSE: To investigate changes of peripheral blood biomarkers and their impact on clinical outcome following treatment with ipilimumab in advanced melanoma patients. EXPERIMENTAL DESIGN: Changes in blood counts and the frequency of circulating immune cell populations analyzed by flow cytometry were...

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Publicado no:Clin Cancer Res
Principais autores: Martens, Alexander, Wistuba-Hamprecht, Kilian, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Capone, Mariaelena, Madonna, Gabriele, Khammari, Amir, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Martus, Peter, Dreno, Brigitte, Ascierto, Paolo A., Wolchok, Jedd D., Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544386/
https://ncbi.nlm.nih.gov/pubmed/27169993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0249
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