Increases in Absolute Lymphocytes and Circulating CD4(+) and CD8(+) T Cells Are Associated with Positive Clinical Outcome of Melanoma Patients Treated with Ipilimumab

PURPOSE: To investigate changes of peripheral blood biomarkers and their impact on clinical outcome following treatment with ipilimumab in advanced melanoma patients. EXPERIMENTAL DESIGN: Changes in blood counts and the frequency of circulating immune cell populations analyzed by flow cytometry were...

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Publicat a:Clin Cancer Res
Autors principals: Martens, Alexander, Wistuba-Hamprecht, Kilian, Yuan, Jianda, Postow, Michael A., Wong, Phillip, Capone, Mariaelena, Madonna, Gabriele, Khammari, Amir, Schilling, Bastian, Sucker, Antje, Schadendorf, Dirk, Martus, Peter, Dreno, Brigitte, Ascierto, Paolo A., Wolchok, Jedd D., Pawelec, Graham, Garbe, Claus, Weide, Benjamin
Format: Artigo
Idioma:Inglês
Publicat: 2016
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5544386/
https://ncbi.nlm.nih.gov/pubmed/27169993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-0249
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