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Surprising toxicity and assembly behaviour of amyloid β-protein oxidized to sulfone
Aβ (amyloid β-peptide) is believed to cause AD (Alzheimer’s disease). Aβ42 (Aβ comprising 42 amino acids) is substantially more neurotoxic than Aβ40 (Aβ comprising 40 amino acids), and this increased toxicity correlates with the existence of unique Aβ42 oligomers. Met(35) oxidation to sulfoxide or s...
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| Publicado en: | Biochem J |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5767168/ https://ncbi.nlm.nih.gov/pubmed/21044048 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20101391 |
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