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Despite its role in assembly, methionine 35 is not necessary for amyloid β-protein toxicity
An important component of the pathologic process underlying Alzheimer’s disease (AD) is oxidative stress. Met(35) in amyloid β-protein (Aβ) is prone to participating in redox reactions promoting oxidative stress, and therefore is believed to contribute significantly Aβ-induced toxicity. Thus, substi...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , , , |
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| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
2010
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908238/ https://ncbi.nlm.nih.gov/pubmed/20345758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06692.x |
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