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Despite its role in assembly, methionine 35 is not necessary for amyloid β-protein toxicity

An important component of the pathologic process underlying Alzheimer’s disease (AD) is oxidative stress. Met(35) in amyloid β-protein (Aβ) is prone to participating in redox reactions promoting oxidative stress, and therefore is believed to contribute significantly Aβ-induced toxicity. Thus, substi...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Maiti, Panchanan, Lomakin, Aleksey, Benedek, George B., Bitan, Gal
פורמט: Artigo
שפה:Inglês
יצא לאור: 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2908238/
https://ncbi.nlm.nih.gov/pubmed/20345758
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06692.x
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