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Despite its role in assembly, methionine 35 is not necessary for amyloid β-protein toxicity
An important component of the pathologic process underlying Alzheimer’s disease (AD) is oxidative stress. Met(35) in amyloid β-protein (Aβ) is prone to participating in redox reactions promoting oxidative stress, and therefore is believed to contribute significantly Aβ-induced toxicity. Thus, substi...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2010
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2908238/ https://ncbi.nlm.nih.gov/pubmed/20345758 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2010.06692.x |
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