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A Key Role for Lysine Residues in Amyloid β-Protein Folding, Assembly, and Toxicity

[Image: see text] A combination of hydrophobic and electrostatic interactions is important in initiating the aberrant self-assembly process that leads to formation of toxic oligomers and aggregates by multiple disease-related proteins, including amyloid β-protein (Aβ), whose self-assembly is believe...

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Detalhes bibliográficos
Main Authors: Sinha, Sharmistha, Lopes, Dahabada H. J., Bitan, Gal
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3382451/
https://ncbi.nlm.nih.gov/pubmed/22860216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn3000247
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