Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins

Amyloidoses are diseases characterized by abnormal protein folding and self-assembly, for which no cure is available. Inhibition or modulation of abnormal protein self-assembly therefore is an attractive strategy for prevention and treatment of amyloidoses. We examined Lys-specific molecular tweezer...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Sinha, Sharmistha, Lopes, Dahabada H. J., Du, Zhenming, Pang, Eric S., Shanmugam, Akila, Lomakin, Aleksey, Talbiersky, Peter, Tennstaedt, Annette, McDaniel, Kirsten, Bakshi, Reena, Kuo, Pei-Yi, Ehrmann, Michael, Benedek, George B., Loo, Joseph A., Klärner, Frank-Gerrit, Schrader, Thomas, Wang, Chunyu, Bitan, Gal
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2011
Soggetti:
Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3210512/
https://ncbi.nlm.nih.gov/pubmed/21916458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja206279b
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi