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Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01

[Image: see text] Many compounds have been tested as inhibitors or modulators of amyloid β-protein (Aβ) assembly in hope that they would lead to effective, disease-modifying therapy for Alzheimer’s disease (AD). These compounds typically were either designed to break apart β-sheets or selected empir...

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Detalhes bibliográficos
Main Authors: Sinha, Sharmistha, Du, Zhenming, Maiti, Panchanan, Klärner, Frank-Gerrit, Schrader, Thomas, Wang, Chunyu, Bitan, Gal
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2012
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386858/
https://ncbi.nlm.nih.gov/pubmed/22860214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200133x
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