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Modulation of Amyloid β-Protein (Aβ) Assembly by Homologous C-Terminal Fragments as a Strategy for Inhibiting Aβ Toxicity

Self-assembly of amyloid β-protein (Aβ) into neurotoxic oligomers and fibrillar aggregates is a key process thought to be the proximal event leading to development of Alzheimer's disease (AD). Therefore, numerous attempts have been made to develop reagents that disrupt this process and prevent...

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Библиографические подробности
Опубликовано в: :ACS Chem Neurosci
Главные авторы: Li, Huiyuan, Rahimi, Farid, Bitan, Gal
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5450937/
https://ncbi.nlm.nih.gov/pubmed/27322435
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00154
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