House Dust Mite–Induced Allergic Airway Disease Is Independent of IgE and FcεRIα

IgE contributes to disease exacerbations but not to baseline airway hyperresponsiveness (AHR) in human asthma. In rodent allergic airway disease (AAD), mast cell and IgE dependence for the induction of AHR has only been observed when mice are immunized with a relatively weak allergen without adjuvan...

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Udgivet i:Am J Respir Cell Mol Biol
Main Authors: McKnight, Christopher G., Jude, Joseph A., Zhu, Zhenqi, Panettieri, Reynold A., Finkelman, Fred D.
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2017
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765415/
https://ncbi.nlm.nih.gov/pubmed/28700253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0356OC
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