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House Dust Mite–Induced Allergic Airway Disease Is Independent of IgE and FcεRIα

IgE contributes to disease exacerbations but not to baseline airway hyperresponsiveness (AHR) in human asthma. In rodent allergic airway disease (AAD), mast cell and IgE dependence for the induction of AHR has only been observed when mice are immunized with a relatively weak allergen without adjuvan...

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Détails bibliographiques
Publié dans:Am J Respir Cell Mol Biol
Auteurs principaux: McKnight, Christopher G., Jude, Joseph A., Zhu, Zhenqi, Panettieri, Reynold A., Finkelman, Fred D.
Format: Artigo
Langue:Inglês
Publié: American Thoracic Society 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765415/
https://ncbi.nlm.nih.gov/pubmed/28700253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0356OC
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