House Dust Mite–Induced Allergic Airway Disease Is Independent of IgE and FcεRIα

IgE contributes to disease exacerbations but not to baseline airway hyperresponsiveness (AHR) in human asthma. In rodent allergic airway disease (AAD), mast cell and IgE dependence for the induction of AHR has only been observed when mice are immunized with a relatively weak allergen without adjuvan...

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Dades bibliogràfiques
Publicat a:Am J Respir Cell Mol Biol
Autors principals: McKnight, Christopher G., Jude, Joseph A., Zhu, Zhenqi, Panettieri, Reynold A., Finkelman, Fred D.
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2017
Matèries:
Original Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5765415/
https://ncbi.nlm.nih.gov/pubmed/28700253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2016-0356OC
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