Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Leishmaniasis is a parasitic infection that afflicts approximately 12 million people worldwide. There are several limitations to the approved drug therapies for leishmaniasis, including moderate to severe toxicity, growing drug resistance, and the need for extended dosing. Moreover, miltefosine is c...

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Detaylı Bibliyografya
Yayımlandı:PLoS Negl Trop Dis
Asıl Yazarlar: Ortiz, Diana, Guiguemde, W. Armand, Hammill, Jared T., Carrillo, Angela K., Chen, Yizhe, Connelly, Michele, Stalheim, Kayla, Elya, Carolyn, Johnson, Alex, Min, Jaeki, Shelat, Anang, Smithson, David C., Yang, Lei, Zhu, Fangyi, Guy, R. Kiplin, Landfear, Scott M.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2017
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764437/
https://ncbi.nlm.nih.gov/pubmed/29287089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006157
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