Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screening

Leishmaniasis is a parasitic infection that afflicts approximately 12 million people worldwide. There are several limitations to the approved drug therapies for leishmaniasis, including moderate to severe toxicity, growing drug resistance, and the need for extended dosing. Moreover, miltefosine is c...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Ortiz, Diana, Guiguemde, W. Armand, Hammill, Jared T., Carrillo, Angela K., Chen, Yizhe, Connelly, Michele, Stalheim, Kayla, Elya, Carolyn, Johnson, Alex, Min, Jaeki, Shelat, Anang, Smithson, David C., Yang, Lei, Zhu, Fangyi, Guy, R. Kiplin, Landfear, Scott M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5764437/
https://ncbi.nlm.nih.gov/pubmed/29287089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0006157
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados